No, none of these sound cards will work with UNi Xonar drivers. The reason is these cards have different audio chipsets with different base drivers than the classic Xonar cards.
I will not make a modded driver for any of these sound cards: ASUS Xonar U1, Xonar U3, Xonar U5, Xonar U7, Xonar AE 7.1, Xonar SE, Xonar EssenceOne, Xonar Essence STU, ROG Xonar Phoebus, and Xonar D-Kara.
You may find some useful information on how to correctly setup your card by reading the Xonar best settings guide that I wrote for the UNi Xonar supported cards and the audio guides we have on the website.
If you are having trouble you could check out ASUS ROG soundcards subforum.
Related articles that may be applicable to your card as well:
- Auxiliary audio applications list - applications for enhancing the audio experience
- Windows 10 audio issues and fixes
- Xonar or other CMI8788 sound card not being detected
- ASUS Xonar cards and AMD Ryzen AM4 motherboards compatibility report
- The case of DPC latency - if you have audio drops/skip for a couple of seconds